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In the following we investigate the effects of a variety of hypothetical drugs that target different cells within the differentiation hierarchy.
In summary, we demonstrate that 11beta-HSD1 mRNA expression is induced within the differentiation process of the murine C2C12 cell line, but also in primary human myoblasts.
RNA isolates were obtained from cells within the differentiation pathways as well as control isolates.
These data demonstrate that Klf4 is a key molecule within the differentiation program of the hypothalamic TRH phenotype [ 37].
This strategy enabled the production of cryopreservable dopaminergic neurons with a high level of efficiency, allowing better control of time management in within the differentiation process.
Determining when this arrest occurs within the differentiation programme would prove useful because it would help to identify potential pathways that might be involved in the initial steps of NB tumorigenesis.
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In contrast, we observed very few xylem cells with secondary walls in bp blr vascular bundles within the differentiation-defective tissue associated with the bp mutation, even at this late stage of development.
This event signifies the migration of cytokines into the spleen, within which the differentiation of Th0 cells takes place.
Importantly, with the progress of differentiation within the CNS, the differentiation potential of the NSCs becomes more restricted, providing the basis for the temporal regulation of differentiation within the developing cortex [1].
Within this context, the differentiation of a population sample from Mozambique from other African populations suggested the presence of a specific South-Eastern component within the continent.
In humans many genes, involved in formation of the CE or in regulation of keratinocyte terminal differentiation, are clustered tightly within the epidermal differentiation complex (EDC), a 1.9-Mb locus on human chromosome 1q21 [7], [8].
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