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Other eligibility criteria included good performance status (WHO grade 0 1), adequate bone marrow reserve (WBC count ⩾3.5 × 10 l−1, platelets ⩾100 × 10 l−1), adequate hepatic and renal function (hepatic enzymes and bilirubin <2 × upper limit of normal, serum creatinine within normality) and an estimated life expectancy of at least 12 weeks.
Mean BACS equivalent scores were within normality ranges for verbal memory (3.37 ± 0.80), digit sequencing (2.69 ± 1.19), symbol coding (2.44 ± 1.55), verbal fluency (2.19 ± 1.60) and Tower of London (2.44 ± 1.55) subtests and borderline pathological for the Token motor test (1.44 ± 1.67).
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For example, for pharmacokinetic, growth, and other data, both the response and the regression model are typically transformed to achieve approximate within-individual normality and constant variance on the new scale; however, the choice of transformation is often made subjectively or by default, with adoption of a standard choice such as the log.
Comparison of lymphocytes subsets phenotype and functional studies was made to data obtained from age-matched healthy subjects (n = 5) used as controls (HC), who displayed CD4+ and CD8+ absolute count and percentage within the normality range: CD4+ 1098/µl (range 797 2365), 45% (range 35.9 66.9); CD8+ 475 (range 447 628), 18.3% (range 17.7 21.3).
For BMD, it was 5.54, falling within the normality range for n = 74 of 4 to 5.87.
In our study, serum albumin levels were lower in the group with steatohepatitis without fibrosis versus the steatosis group but still within the normality range.
The damage induced by chemotherapy could impede a complete catch-up growth, even if our survivors reached a FH within the normality.
As shown in this table, the q value of P300SP was 6.02, that for P300V was 5.23, and that for age was 5.04--all falling within the normality range for n = 92 of 4.15 to 6.05.
GGT activity was higher in individuals with steatohepatitis (significantly for steatohepatitis with fibrosis versus steatosis); ALT and AST liver enzyme activities were within the normality standard as well as AP levels.
Normality of within-group errors was tested by examining normal probability plots of the random effects and residuals for each model.
Fluids (crystalloids and colloids), vasopressors (norepinephrine) and inotropic agents (dobutamine) were provided according to individual needs, in order to maintain the Intrathoracic Blood Volume Index (ITBVI) within the range of normality (800 1000 ml/m), a normal cardiac index value, and mean arterial pressure (MAP) > 65 mmHg.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com