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It is noteworthy that all these T-DMRs were located within few kb from CGIs.
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Complicating interpretation of these observations is the fact that a significant number of genes expressed specifically at the 2C stage initiate transcription within MERVL LTRs, such as Zfp352[ 53] and Tdpoz4[ 55], or are located within a few kb of a MERVL LTR [ 11, 12].
Scoring amplification of each product followed by additional PCR reactions for progressively narrower intervals based on results of the initial scan permitted us to map breakpoints to within a few kb (Figure 4C).
Moreover, it has been demonstrated that the position of transcription factor binding sites often lie within a few kb 5' of the basal promoter [ 21].
Sliding window plots of the densities of high GC-content PPTs in the two regions in which multiple human hot spots have been mapped showed that peaks in density often occur within a few kb of hot spots.
LD decay, the rate at which LD breaks down, occurs slowly in commercial maize germplasm [ 9- 11]; in numerous other germplasm lines, including landraces, it occurs within a few Kb because of high rates of recombination [ 12- 16].
In addition, the unique pattern of linkage disequilibrium (LD) in maize, where LD decays within only a few kb in a population of diverse inbreds, makes it suitable for LD-based, high-resolution association mapping [24].
The ICR can lie within the lncRNA, a few kb upstream of the promoter or at the lncRNA promoter.
However, embedded speech recognition only authorizes few KB of memory, few MIPS, and small amount of training data.
These regions are mostly a few kb in size (mean = 6.6 kb), with 11 regions larger than 10 kb and 3 larger than 30 kb.
Although DHSs are generally a few Kb in length, DNase footprinting (which combines deeply sequenced DNase-seq data with motif information) can help more precisely identify the critical nucleotides for TF occupancy within a DHS site [ 26, 27].
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