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The primary efficacy end point was change from baseline A1C at week 16 versus placebo across different doses within each schedule (weekly, biweekly, and monthly).
The proportion of subjects achieving the ADA target A1C (<7.0%) at week 16 increased with increasing doses of albiglutide within each schedule; similar proportions of subjects achieved target A1C at the highest albiglutide dose among the three schedules.
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Within each vaccination schedule group, the RTS,S/AS01E formulation consistently yielded higher peak anti-CS responses as compared to RTS,S/AS02D.
Within each dose schedule, albiglutide was associated with generally dose-dependent A1C reductions that were significantly different from placebo.
Median Latencies 1 and 2-8 were computed separately for each rat within each VI schedule and epoch, and then averaged within strain (mean median latencies).
After 16 weeks, albiglutide significantly reduced A1C in a generally dose-dependent manner within each dose schedule (Table 1) (Fig. 1 A).
A Simon's 2-stage optimal design was implemented within each treatment schedule with the assumed response rate for the null hypothesis of po = 11%%, the assumed response rate for the alternative hypothesis of p1 = 24%%, a targeted one-sided alpha = 0.05, and power = 80%%.
This classification took into account that, within each VI schedule, the duration of the first interval to reinforcement could only be cued by the discriminative tone, whereas the duration of subsequent intervals could also be cued by the duration of the preceding intervals.
Within each six-month interval, each scheduled NT PCDS CVD preventive service (N = 20) was coded as delivered (1) or not (0).
Third, we might consider how the active learning tools were situated within each course's schedule and institutional resources.
Within each PR session, the schedule of reinforcement was increased in the following pattern: 1, 2, 4, 6, 9, 12, 16, 20, 25, 30, etc. [40], [43].
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