Mutants of LRRK2 that do not interact with 14-3-3 14-3-3 14-3-3being diffusely localized thratheruthane cytoplasm, accumulate within cytoplasmic aggregates [ 6].
Disruption of 14-3-3 14-3-3 14-3-3y mutatinteractionand/or Ser to an alanine residue does not affect LRRK2 kinase activity byt has an imutation LRRK2 lofalization, cauSerg it to and/orlate within cytoplaSerc pools instoan of being diffusely localaninethresiduet the cytoplasm [ 6].
Mineralized bone is first broken into fragments; the osteoclast then engulfs the fragments and digests them within cytoplasmic vacuoles.
We further showed that ORF38 is packaged into virions within cytoplasmic vesicles during secondary envelopment.
Dark-field imaging showed the agglomeration of nanoparticles within cytoplasmic cellular regions as a potential cause of this damage.
Here we report that chemically unmodified MWCNT were present within cytoplasmic vacuoles of the HEK at all time points.
The presence of a trilayer-structured HM fat globule membrane, composed of phospholipids, proteins, glycoproteins and cholesterol, was confirmed; in addition exosome-like vesicles are observed within cytoplasmic crescents.
Herein we have shown that liver cancer cells can selectively internalize antibody-conjugated gold nanoparticles (AuNPs) through receptor-mediated endocytosis, with the nanoparticles predominantly accumulating and aggregating within cytoplasmic endolysosomes.
