In some ways, Mr. Newsom's withdrawal raises questions about California's political system, in which candidates for governor must raise tens of millions of dollars to be competitive because of the sheer size of the state and the cost of television advertising.
Mr. Wheeldon's withdrawal leaves a question mark over the company's ability to continue to attract audiences and donors.
Strikingly, among the four EP3 receptor splice variants detected in HT-29 cells, only those linked to Gi-proteins were up regulated in response to serum withdrawal, raising the question as to why CRC cells should choose to up regulate expression of G1-coupled receptors in the absence of proliferative signals.
The Vioxx withdrawal raised important questions about the role of direct-to-consumer advertising in creating "blockbuster" drugs.
"Whatever our withdrawals are, the question is: Are you giving these folks a safe haven?" said David Kugler, the president of Monument.
Moreover, MSF's withdrawal raises critical questions about what aid workers consider as acceptable in order to maintain access to affected populations, as well as the consequences of these choices.
The withdrawal, based on questions raised about Mr. Modi's human rights record, has spurred an animated debate about freedom of speech and Mr. Modi's leadership credentials in India and among the Indian diaspora.
Its withdrawal raises serious questions about the Gulf governments' ability to overcome old political rifts for the sake of economic and financial integration.Two weeks ago the Gulf rulers, making reference to Maastricht (the Dutch town where the euro was born), decided that the planned central bank would be based in Saudi Arabia.
Their reasons for withdrawal were not questioned, and it would have been unethical to pressure them.
Of these individuals, 49 attended the SPACE programme alone, while 81 stated that they attended with a partner (that this figure is an odd number most likely results from one parent in a couple not consenting to take part in the study, withdrawals, or the question being incorrectly answered by a participant).
