Exact(5)
This study aimed to determine if a sub-chronic low (sub-anesthetic) dose of ketamine could be used to augment the antidepressant effects of the widely used antidepressant fluoxetine (Prozac®) in adult zebrafish, employing an ethanol withdrawal model.
Mice were chronically treated with nicotine for 14 days and physical and affective nicotine withdrawal signs were measured using a spontaneous nicotine withdrawal model and conditioned place aversion (CPA) following pre-treatment with LY2456302, administered orally.
The ovarian-steroid withdrawal model [47] is one model, but it does not allow for an exploration of offspring effects due to required ovariectomy in the females.
We chose to use the spontaneous withdrawal model in this study because its course more closely follows that observed in the clinic than other withdrawal models, such as the naloxone-precipitated withdrawal model.
These previous studies reported the anxiolytic properties of MPEP in normal rats, while our study is reporting the anxiolytic properties of MPEP using an ethanol withdrawal model for the first time.
Similar(54)
In a cyclic operations with CO2 withdrawal, our model of the process predicts a swing capacity of 5% (wt).
In a cyclic operations with CO2 withdrawal, our model of the process predicts a swing capacity of 5% (wt.) when withdrawing CO2 at 20 bars, and 2% when withdrawing CO2 at 80 bars (supercritical fluid).
Our previous study demonstrated that osteogenic effects imparted by the extract of Dalbergia sissoo in the estrogen withdrawal osteoporotic model were due to the presence of a novel analog CAFG present in maximum amount.
Different hyperalgesic states including acute inflammation, acute opioid withdrawal and models of systemic illness and acute stress are associated with an increase of ON cell firing and suppression of OFF-cell disharge [77].
Variables that were not associated with the outcome in multivariable analyses and whose withdrawal from the model did not change the OR estimate for at least one other variable in the model by ≥ 10% we did not retain in the final multivariable model.
In this model, withdrawal of oral doxycycline induces the expression of TGF β1 transgene.
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