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But Margaret Gilbert [2000] has objected that reductive approaches overlook the mutual obligations between participants essential to shared activity: each participant is obligated to the others to do his or her share of the activity, and unilateral withdrawal constitutes a violation of this obligation.
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Peter Crowley, the Unicef representative in Afghanistan, feels this is a crucial moment for Afghanistan, and is sure that the current situation, with rising violence and troop withdrawal imminent, constitutes a potential "perfect storm" that could obliterate the hopes of the children they have spent years trying to help.
Agitated delirium syndromes, such as ethanol withdrawal, may constitute genuine medical emergencies as they have potentially disastrous hemodynamic and metabolic consequences and may become an indication for therapeutic musculoskeletal paralysis [ 29].
Clinical and preclinical evidence indicates that chronic alcohol use and withdrawal experience constitute potent stressors, leading to HPA axis activation and long-lasting dysregulation of the neuroendocrine stress response as well as perturbations in sympathetic nervous system activity.
And as the godmother of modern improvisation, Viola Spolin said, "To react is protective and constitutes withdrawal from the environment.
Between randomisation and the end of the trial, there were many decisions made by clinicians to discontinue or change allocated treatments; again this did not constitute withdrawal from this pragmatic trial.
Trump's withdrawal from the climate agreement constitutes an impeachable offense.
Would withdrawal be total?
Inclusion of a representative patient spectrum and explanation of selection criteria or withdrawals did not constitute a limitation of any study.
However, a Member State's notification of its intention to withdraw does not constitute that State's withdrawal.
Similarly, differences in rater opinion regarding what constitutes an 'adequate' description of withdrawals, inclusion/exclusion criteria or adverse effects led to poor agreement on these questions.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com