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Exact(14)
We will withdraw patients only if patients withdraw consent for participation.
Secondly, we had a priori decided to withdraw patients when their plasma glucose exceeded 16 mM.
It would not be ethical to withdraw patients in need from a treatment that has been found effective.
For example, physicians may have been less likely to withdraw patients with perianal disease or rectal disease.
The investigator also has the right to withdraw patients in case of safety issues or protocol deviations.
Investigators who receive incentives based on the numbers of participants completing a trial may similarly be reluctant to withdraw patients with adverse effects.
Similar(46)
Mean ICU stay was, respectively, 10.3 ± 13.7 days and 11.1 ± 11.7 days for withheld and withdrawn patients.
Prematurely withdrawn patients are not replaced but undergo the procedures scheduled for the last visit, to the extent possible.
There were no additional evaluations for withdrawn patients.
No replacement for withdrawn patients will be performed.
To ensure adequate inclusion, withdrawn patients will be replaced by additional inclusions.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com