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The βInt for reach and withdraw conditions were not significantly different.
The corresponding scalp topographies in the reach and withdraw conditions were also remarkably similar.
The amplitudes of the main LEP waves were not different in the reach and withdraw conditions (N1: P = 0.81; N2: P = 0.072; P2: P = 0.91).
The position of the 2 buttons was adjusted in each subject to achieve similar response times in the "reach" and "withdraw" conditions.
Figure 4 shows the time course of the coefficients of the intensity and response time regressors (βInt and βResp, respectively), for the reach and withdraw conditions.
Crucially, the βResp in the reach and withdraw conditions were significantly different the trial-by-trial variability of LEP amplitude better predicted response times in the withdraw condition than in the reach condition (P < 0.05; Fig. 4, lower panel).
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Red line shows that GF reduces TMRE staining under serum withdraw condition, indicating that GF decreases mitochondrial membrane potential.
(2) MCF-7 cells were cultured long-term under SERM-treated or estrogen withdrawn conditions (to mimic aromatase inhibitors), and then injected into mice to generate endocrine-resistant xenografts.
In the other 2 blocks ("withdraw" condition), the button was placed approximately 10 cm from the body, at midline (i.e., ∼30 cm closer to the body with respect to the hand).
This adjustment was based on a preliminary recording of response times to 20 stimuli (10 in the "reach" and 10 in the "withdraw" condition) delivered at an energy level halfway between the low and the high energies used in the main experiment.
Subjects were instructed to react as fast as possible when they felt the laser stimulus, by releasing the switch and pressing a response button that, in contrast to Experiment 1, was always placed approximately 10 cm from the body, at midline (i.e., as in the "withdraw" condition of Experiment 1).
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com