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A pastry shop with undigested material.
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The vesicles are often considered as lysosomes, endosomes, and/or autophagosomes that are engorged with undigested materials.
These data suggest that the presence of GROD-like inclusions and AVs with undigested materials such as GROD-like inclusions may be a potent inducer of autophagy in neuronal cells.
Dysfunction of lysosomal proteins is often associated with intralysosomal storage of undigested material due to impaired hydrolytic or transport activity (Futerman and van Meer, 2004).
Along with his own reflections, which range in length from one sentence to several pages, the convolutes are stuffed with undigested research material: passages from historical sources and Benjamin's contemporaries in literature and philosophy.
Mice homozygous for mutant V394L glucocerebrosidase and deficient in saposin C, used to model neuronopathic Gaucher disease, exhibit punctate p62/SQSTM1 accumulations in neurons and astrocytes, and sequester undigested material in vesicles within axons, consistent with an accumulation of autophagic substrates.
The fate of the internalized cell's undigested material awaits further investigation.
They learn how to read and draw inferences from undigested material.
The quantity of undigested material remaining at the end of 120-minute in vitro digestion correlated significantly with the percentage of particles greater than 2000 μm in masticated rice.
The TAL-ezh1 injected embryo contains undigested material (arrow at 311 bp), indicating that the BamHI diagnostic restriction site has been disrupted.
To simulate blockages and impedance of debris generated by cell shedding, infections, adhesions on the wall and undigested material, a drag force porous media model is utilized.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com