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The underlying event rates for experimental arms with underlying effects A-D were found by adding on the corresponding treatment effects shown above.
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The posterior distributions of the treatment effect (i.e. difference in change from baseline) and expected change from baseline by treatment were summarized with the median and 95% credible intervals (95% CI) reflecting the range of true underlying effects with 95% probability.
Future studies thus need to demonstrate consistent effects for a range of clearly defined outcomes by using valid measures across several different influenza seasons, with sufficient power to detect true underlying effects.
Estimates were sensitive to assumptions with respect to the magnitude of alcohol's underlying effects on condom use, antiretroviral therapy adherence, and sexually transmitted infection prevalence.
But whatever acupuncture's underlying effects turn out to be, experts say its gradual merger with conventional medicine will have broad implications, eventually opening the door to closer examination of other popular therapies that lie outside the mainstream.
In particular, the distinction between activators and inhibitors is of fundamental importance with respect to the underlying effect of a metabolic enzyme regulation.
The weight function depending on the p-value for the hypothesis that the true underlying effect is zero is defined as with suitably defined constants a and b.
"If a secular government can be established in Iraq with Sistani's blessings, it's going to have a huge underlying effect next door".
Because of this, our significant associations with age for different pathways could be related as a common underlying effect on a given set of genes.
Relative change can dramatically exaggerate the underlying effect.
Random effect meta-analysis assumes a different underlying effect for each study and takes this into account as an additional source of variation, resulting in a summary effect measure with wider CI.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com