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In our case, the automedication by Nestosyl® with unawareness of the potential risks and the limitations of use of this treatment caused methemoglobinemia: a potentially life-threatening complication.
With unawareness, we hand our life over to our habits".
In contrast to previous findings, living alone was not significantly associated with unawareness of present cognitive impairment in our study [ 26].
Psychological defensiveness in psychosis is associated with unawareness of having a mental disorder, unawareness of the effects of antipsychotic medication and inability to attribute symptoms to a mental disorder [ 26].
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As yet, neuroimaging data have compared diabetic subjects with hypoglycemia unawareness only with nondiabetic control subjects, so the effect of diabetes alone remains uncertain.
A total of 31 patients with hypoglycemia awareness and 19 patients with hypoglycemia unawareness were identified, with insulin regimens available in 23 and 13, respectively.
Patients with hypoglycemia unawareness were older, with longer diabetes duration.
Type 1 diabetic patients with hypoglycemia unawareness were older, with longer diabetes duration, more severe hypoglycemia, and lower A1C than patients with hypoglycemia awareness, consistent with published literature (7).
The epinephrine response to hypoglycemia in patients with type 1 diabetes with hypoglycemia unawareness was greater after the use of real-time CGM with low glucose alarms than with standard medical therapy alone.
Adolescents with type 1 diabetes with hypoglycemia unawareness underwent hyperinsulinemic hypoglycemic clamp studies at baseline to determine their counterregulatory hormone responses to hypoglycemia.
To determine whether real-time continuous glucose monitoring (CGM) with preset alarms at specific glucose levels would prove a useful tool to achieve avoidance of hypoglycemia and improve the counterregulatory response to hypoglycemia in adolescents with type 1 diabetes with hypoglycemia unawareness.
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