Sentence examples for with trail from inspiring English sources

Combination of CDK9 inhibition with TRAIL effectively induced apoptosis even in highly TRAIL-resistant cancer cells.

However, co-treatment of A549 cells with TRAIL and AFMC markedly increased the cytotoxic effects of TRAIL in a dose-dependent manner compared to treatment with TRAIL or AFMC alone.

However, the Smac mimetic potentiated TRAIL-induced apoptosis compared with TRAIL treatment alone (1.7-fold), confirming the cooperative effect of IAP antagonists with TRAIL versus Smac mimetic-treated samples).

Increased expression of decoy receptors and decreased DR4/DR5 expression have been correlated with TRAIL resistance, although other studies indicated that the expression levels of TRAIL receptors do not correlate with TRAIL sensitivity.

As VEGF expression was affected in A172 cells treated with TRAIL, we first attempted to measure changes in VEGF mRNA amounts by Northern blot analysis in cultures treated with TRAIL.

Thus, cells that are characterized by a death resistant phenotype when treated with TRAIL may convert into highly aggressive tumours that exhibit an increase in proliferation and metastatic capacity when stimulated with TRAIL [ 28, 29].

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The use of TPGS in combination with TRAIL and endostatin had synergistic antitumor effects.

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These insights will direct rational design of drug combinations with TRAIL receptor ligands to maximize DISC signaling.

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