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A concern with this upfront approach is the potential for rebound tumour growth during the treatment interruption for nephrectomy [ 19].
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In the revision (paragraph 7 of the Results section) we now state this upfront along with the rationale for simulating both 1D and 2D conditions along a 1D track.
However, this upfront selectivity combined with incomplete follow-through in reflex testing may reduce the sensitivity of the testing overall.
Although such a process would be associated with additional upfront resource investment, this appropriation may be modest in comparison with the downstream costs associated with maintenance of poorly performing sites, failed clinical trials, and the global health and economic burden of HHF.
Armed with this information, you can then negotiate with doctors upfront to accept the insurance company payment or ask if they will negotiate with the insurer directly.
However, this fee must be agreed with you upfront, so there shouldn't be any hidden surprises.
However, this would not influence the conclusions of this paper that survival benefit with upfront surgery especially in subset of patients with tumor ≤25 mm in size and ≤1 involved peripancreatic LN is dependent on achieving an R0 resection.
"I'm kind of putting it on my forehead and being very upfront with this because this isn't something that I want to hide," Franzone said.
"Having the courage to be upfront with this kind of thing has been unlike anything I've ever experienced," he said.
"I have been very upfront with this committee about my views and about how serious I take it, and that I would set aside any personal or religious views if I were to be confirmed".
With an upfront cost of £455 for the phone this gives a total cost of £707 over the two-year contract period.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com