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Currently, clinical studies are performed to test safety of anti-angiogenic therapy with this cyclic RGD-peptide in humans.
Large outbreaks of rodents (known as "ratadas") are associated with this cyclic phenomenon (10, 11 ), with existing chronicles as old as the conquest and Spanish colonization of the country (12 ).
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Thus, both single and double suture could stabilize the meniscal tear with small stress under this cyclic loading condition.
When these cells were pre-incubated with micromolar concentrations of this cyclic RGD peptide before being exposed to fluorescently-labeled disintegrins, the cyclic RGD treatment also prevented the binding of both disintegrins.
With this purpose, cyclic voltammetry and chronoamperometry techniques were combined with a new configuration of an electrochemical mass spectrometry (EC-MS), which allows high detection sensitivity with low amount of catalysts.
Consistent with this hypothesis, cyclic equibiaxial stretching at 0.01Hz, which is predicted to generate a negligible perturbation in fiber tension (cf. Fig. 2), did not cause a significant change in cell spreading area (Fig. 3C E and Video S2).
Whereas with the cyclic increased continuously, the efficiency decreased.
These results coincide well with the cyclic voltammetry measurements.
No intermediates were recovered from incubations with the cyclic hexamers except for a nicked Lfc5.
can be implemented on a SLIM-based architecture, as with the cyclic TWIMS device described above.
36 How does the complex organization of chromatin cope with the cyclic regulation of circadian genes?
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