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More recently, in December 2014, another anti-PD-1, nivolumab, was approved by the FDA for patients with advanced melanoma with the same indication as pembrolizumab.
These pregnant patients were matched 1 1 with 20 pregnant controls with the same indication for colonoscopy but who did not undergo colonoscopy due to pregnancy.
The comparative head to head design, with bupropion as the reference, allowed us to compare varenicline with a drug with the same indication and no known cardiovascular risk.
The strength of the study is that it describes surgical outcome for a specific tumor type in a consecutive series of patients with the same indication for surgery.
We estimated rates of vascular events within groups of patients with the same indication for antiepileptic drugs, minimising the potential for confounding by indication.
By design, this bias was minimised by estimating the risk within groups of patients with the same indication and by choosing a treated comparator group.
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Appropriate as defined in the legal framework of Social Code Book V means as compared with other treatment strategies within the same indication area.
As we had mentioned in our previous work [ 12], we compare the new drug to existing drugs with exactly the same indication.
Stents have been used in the benign setting with the same indications.
We analyzed the French drug agency reports and SPCs of these drugs, together with those of other drugs for the same indication, with which they were to be compared.
A tool providing physicians with comparative drug information would be useful, if it provided both synthetic and detailed information about new drugs, comparing them with existing drugs for the same indication.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com