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Discover Ludwig"with the onset" is a perfectly correct and usable phrase in written English.
You can use it when referring to the beginning or start of an event, change, or process. For example, "With the onset of winter, we experienced a lot more snowfall than usual."
Exact(60)
With the onset of fall came rain.
But the plan fizzled with the onset of the Depression.
The situation has worsened with the onset of the global financial crisis and the recession.
With the onset of cooler weather, it's the perfect time to harvest your oat recipes.
With the onset of the Cultural Revolution in 1966, Western music was condemned as bourgeois.
All that changed rapidly with the onset of the credit crisis last year.
With the onset of the First World War, Kandinsky became an enemy alien in Germany.
Colour started to drain away with the onset of news of Marcos thuggery and debauchery.
"The whole drug discovery process is changing with the onset of genomic research," he said.
Falciani's flight to France coincided with the onset of the global financial crisis.
With the onset of summer, schools are closing and fund-raising is winding down.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com