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The variance between countries with respect to the attitudinal traits would appear to vary somewhat across scales, with the largest variability occurring for the Future A (FUTA) scale, and the lowest for the Environment (ENV) scale; moreover the variances within country are also noticeably different across scales, with the same scales occupying the extremes.
The top 500 probe sets with the largest variability in the data were chosen.
Significantly, the gene encoding the mouse FGF8 was found to be the only gene in all three sets of genes with the largest variability (Fig. 5A).
Moreover, we found that 14.3% of the CpG sites in CFs with the largest variability upon TGF-β1 treatment (Supplementary Table 3A and Supplementary Material, available at Carcinogenesis Online) overlapped the 1452 differentially methylated CpG sites in CFs and TAFs.
The data were obtained from the Bioconductor package 'breastCancerTRANSBIG' [ 39], and processed to remove duplicate probes mapping to the same Entrez Gene ID (probes with the largest variability are retained).
Agreement was assumed to occur when the absolute difference between the scores of adolescents and their parents was less than or equal to 0.5 SD of the score with the largest variability (this group is referred to as AGREE).
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In summary, responses of individual pyramidal cells were quite variable; consistent with the large variability of photocurrents we measured (Fig. 1B).
55 of these 356 loci overlapped with ERVs and these showed the largest variability in DNA methylation across the mice.
With RNA-Seq data, however, the largest variability is known to come from biological stochasticity rather than from technical inaccuracies [ 29, 30].
In OHTS, subjects in Class 4 (with a moderate mean IOP and the largest variability) had similar risk as those in Class 5 (with a higher mean IOP and much less variability), but showed a higher risk than those in Class 3 (with the mean IOP comparable to Class 4 but with much less variability).
Their findings were consistent with the large variability in natural durability reported for plantation-grown redwood from New Zealand (Jones et al. [2011], [2014]).
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