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The ability to form a specific foscarnetRTP/T complexes with the CBB and CTB templates coupled with the inability to detect a specific foscarnet-induced cross-link with the CBT template suggests that formation of stable foscarnetRTP/T complexes is dependent on sequence context.
The small sample size may be associated with the inability to detect potential differences in certain metabolites.
Recent studies have indicated that a lack of sequencing depth is typically associated with the inability to detect lowly expressed genes [ 46, 49- 51].
In conjunction with the inability to detect outcome differences between groups, TNBC tumors from AAW and CW were molecularly similar, with PCA failing to separate gene expression patterns by population.
Proteins undergo thermally activated conformational fluctuations among two or more substates, but a quantitative inquiry on their kinetics is persistently challenged by numerous factors, including the complexity and dynamics of various interactions, along with the inability to detect functional substates within a resolvable time scale.
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Similarly, the increased protection for the identification of false positives achieved in this study by the elimination of SNPs with MAFs lower than 0.1 is offset by the inability to detect real resistance genes with low allele frequencies.
The results of the CAB investigation suggest that, soon after takeoff, Peterson became disoriented due to the unfamiliar way the aircraft's attitude indicator depicted pitch, combined with an inability to find a point of visual reference on a starless night with no visible lights on the ground and the inability to detect the horizon.
Elevation of cleaved caspase 8 indicated that some of the observed loss of mitochondrial potential stems from the extrinsic pathway which may in turn be amplified through activation of caspase 9. Of note is the inability to detect cytochrome C with hemozoin despite the observed disruption of mitochondria equivalent to that observed after cross linking the death receptor CD95.
The study by Völkel et al. (2002) has been repeatedly cited as evidence for rapid clearance of unconjugated serum BPA in adult humans, based on the assumption that the inability to detect unconjugated BPA with an insensitive assay indicated that all unconjugated BPA had been very rapidly metabolized.
The experimental intractability of this problem is sharpened by the inability to detect early responder cells even with the extremely sensitive assay that we used.
A significant proportion of clinical trials still focus on the mild-to-moderate disease stages due to the inability to detect Alzheimer's disease early with high specificity.
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