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It has previously been demonstrated that actively translating ribosomes can efficiently inhibit poliovirus RNA synthesis [56] and that the interaction of the viral polymerase precursor 3CD with the 5' end, in combination with the cellular protein PCBP2, inhibits translation promoting negative strand RNA synthesis [57].
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"Begin with the end in mind".
Start with the end in mind.
Finally, and most importantly, visualising the end user in combination with imagination-based visualisation led to designs that were significantly more appealing to the customer.
PTB binding to the 5' end, probably in combination with other host cell or viral factors, prevents translation initiation and ribosome recruitment (Fig 12d) promoting the synthesis of viral RNA (Fig 12e).
To that end, in combination with other members of the original Dojo team, Heretix sees its official unveiling today, with a mission to help companies grow without being tied to outside agencies or consultants.
RAD51 binds the DNA ends, in combination with associated proteins including BRCA2, RAD52, RAD54, RAD54B, and the RAD51 paralogs (RAD51B, RAD51C, RAD51D, XRCC2, and XRCC3).
In the end, the combination proved irresistible.
In the end, the combination of sacrifice and new products is supposed to save the newspaper.
There they are administered after debridement and refreshing of the fracture ends, often in combination with autologous bone grafts, during the newly created initial pro-inflammatory phase of bone healing.
To this end, fotemustine, in combination with sequential immunotherapy for treatment of metastatic ocular melanoma, resulted in a median survival of one year (95% confidence interval 347 and 390 days); the overall survival of patients experiencing an objective benefit of this therapy in the form of an objective response or a stable disease was 19 months.
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