Exact(7)
With the cohesion of the eurozone at stake, the whole world will be watching the show.
We may save the ontology integration details along with the cohesion scores.
Homolog of Afd1 encodes protein associated with the cohesion complex, which establishes sister chromatid cohesion [ 33- 35], while RPA70 is implicated in replication, repair, and transcription [ 36].
By following the basic idea of the proof of Theorem 4 we can show that Algorithm 3 builds an optimal integrated ontology with the cohesion matrix provided from Algorithm 2. We omit the proof for succinctness.
This suggests that inefficient establishment of sister chromatid cohesion results from a defect in the replication machinery rather than a structural problem with the cohesion apparatus, highlighting the intimate connection between DNA replication and sister chromatid cohesion.
This is in agreement with the cohesion defect already observed in the yeast orthologue mutants, csm3 (Marston et al, 2004; Mayer et al, 2004; Xu et al, 2004) and ctf4 (Hanna et al, 2001; Petronczki et al, 2004; Zhou and Wang, 2004; Xu et al, 2007).
Alabrudzinska et al. (2011) showed by FACS analysis that diploid S. cerevisiae strains lacking Ctf18p (a protein involved in loading PCNA on DNA and interactions with the cohesion complex) have very high levels of chromosome loss, with some isolates having the DNA content of haploid or near-haploid strains by FACS analysis.
Similar(1)
Fracture walls were also lined with ash, the cohesion of which was likely aided by the same condensing vapors.
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