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With the aim to recapitulate the pipeline of MPSII neuropathology, we analyzed the differentiation pattern of NSCs derived from the SVZ of early symptomatic IDS-ko mice in comparison with a time-course analysis of MPSII mouse brains at different stages of the disease and with a human Hunter cortex.
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We acknowledge that this is a valid point, yet with the aim to recapitulates the natural evolutionary process of gene dosage changes we used similar increments in gene copy number for both rare and abundant tRNA.
The 3D models aim to recapitulate the tumor microenvironment, which has a critical role in the pathogenesis of ovarian cancer.
In an effort to improve these properties tissues grown in vitro are often subjected to mechanical stimuli that aim to recapitulate the in vivo physiology.
In vivo models aim to recapitulate OA-associated processes and lesions in the whole animal.
Origin of life chemistry experiments often aim to recapitulate reactions or molecules/molecular processes that resemble species that were present in the last universal common ancestor (LUCA) or that could have eventually led to LUCA.
Therefore, current vaccine strategies should at least aim to recapitulate these findings in Phase I human studies before efficacy testing.
Importantly, recent advances in our understanding of the physiology of immune responses offer new avenues to design and test candidate adjuvants, based on either synthetic or natural molecules, with the aim to mimic and recapitulate pro-inflammatory signals initiating both innate and adaptative immune effector mechanisms.
An in vitro experimental model aiming to recapitulate the clinical conditions was generated in order to study the effect of three dental materials on dental mesenchymal stem cells.
This review aims to recapitulate the vascular anatomy and network of RFFF as well as shed light on deep vein as a reliable venous drainage system.
This model aims to recapitulate the heterogeneity of GBM and its environment, which is observed in patients.
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