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Downstream of Smo the signal culminates with the activation of the Ci/Gli transcriptional activators and removal of the Ci/Gli repressors.
In a previous study, the CuE activated the caspase-dependent pathway, coinciding with the activation of the mitochondrial pathway in bladder cancer cells.
In a previous study, CuE was shown to activate the caspase-dependent pathway, coinciding with the activation of the mitochondrial pathway in bladder cancer cells.
The effect was correlated with the activation of the PI3K/Akt signal pathway.
In cultured human endothelial cells, physiological levels of NO prevent apoptosis and interfere with the activation of the caspase cascade.
The release of the drug occurs concomitantly with the activation of the fluorophore to its Turn-ON state.
At the heart stage, PEAR1 transcription is enhanced in ult cells underneath the shoot apical meristem, which correlates with the activation of the cytokinin response in this domain (n, arrowheads).
We hypothesized that programmed offspring hypertension is associated with the activation of the adipose tissue RAS in the offspring of obese rat dams.
Finally, cytochrome c is released from the mitochondria of Purkinje cells in a time course consistent with the activation of the mitochondrial pathway of apoptosis.
The molecular mechanisms that underlie the beneficial effects of Sirt1 on DN correlate well with the activation of the Nrf2/ARE antioxidative pathway.
Concomitant with the activation of the autophagic pathway, TM cells grown under oxidative stress conditions displayed, however, reduced cathepsin (CTS) activities, reduced lysosomal acidification and impaired CTSB proteolytic maturation, resulting in decreased autophagic flux.
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