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But what surprised them was that while one person with the aberration might get one disorder, a relative with the same mutation got a different one.
Then the data were input into the optical design software ZEMAX and the crystalline lens's shapes were optimized with the aberration as the merit function.
One such sample is the incommensurate grain boundaries found in polycrystalline single-layer graphene [32, 40, 41]. Figure 6a shows the exit wave phase of a graphene grain boundary with a large field of view after applying the aberration correction described in this work, with the aberration function inset and the numerical coefficients given in the "Appendix".
Among the patients with 17p deletion one was considered borderline (10 15% cells with the aberration).
In Genomic Workbench 7.0, the genomic intervals are constructed from the data obtained with the aberration detection algorithm (Z-score algorithm) using a 2-Mb sliding window with a threshold at 0.2.
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All this demonstrates that, under the high resolution conditions (NA = 1.4) here used, this methodology is able to successfully deal with the aberrations present in the imaging system.
By applying metaphase analysis a different picture emerged with respect to the aberration yield, i.e. more aberrations were detected in cells exposed to Fe-ions than in those irradiated with Cr-ions.
This combined image also illustrate the role of the sample geometry in the spatial variations of aberrations, with the largest aberrations located around heterogeneities such as the boundaries between the region containing neuron bodies and the dense neuropil regions.
Consider linear regression of the horizontal component of the aberration with horizontal position in the image.
These observations suggest that BPIQ-induced growth inhibition is associated with G2/M arrest and the aberration of polyploidy.
The numerical comparisons are then made between the ray tracing, the aberration expressions with the linear and with third-order accuracy of the aperture ray.
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