Sentence examples for with superior safety from inspiring English sources

Phase 3 trials have demonstrated similar or superior efficacy combined with superior safety for the short-acting pentasaccharide fondaparinux, as compared to low-molecular-weight heparin.

Despite the introduction of several extended-spectrum triazoles and echinocandin antifungal agents with superior safety, spectrum, and potency, the incidence of invasive Candida infection and the associated mortality have not decreased over the past two decades [2].

He says its all-wheel-drive platform makes it perfect for all kinds of flat surfaces, with superior safety to boot – and as Top Gear's James May proved in Series 19, it isn't afraid of a bit of mud: Most readers will stick to purpose-built off-road vehicles if a country-hopping expedition were on their calendar.

Given all the aforementioned issues with IVPR, enteral potassium replacement (EPR), with its superior safety profile, may be a better alternative to IVPR.

Sindbis replicon-based vaccine vectors are designed to combine the immunostimulatory properties of replicating viruses with the superior safety profile of non-replicating systems.

In 6-month follow-up, the DREAMS-2G showed a substantially improved performance with a superior safety profile to that of its DREAMS-1G precursor, i.e., no thrombosis or cardiac death up to 6 months (Haude et al. 2016b).

Enteral potassium replacement (EPR), with its superior safety profile, may be a better alternative to IVPR.

Capecitabine, an oral fluoropyrimidine, was at least as active and effective as 5-FU in the first-line treatment of mCRC in Phase III trials, with a superior safety profile 10– 12. Similarly, a combination of capecitabine and oxaliplatin (Xelox or Capox) but not irinotecan (Xeliri/Capiri) was at least as effective as its infusional counterpart, FOLFOX 13191319

Different phase III trials have shown that capecitabine is at least as active and effective as 5-FU in the first-line treatment of mCRC, with a superior safety profile (Hoff et al, 2001; Van Cutsem et al, 2001; Cassidy et al, 2002).

Finally, pimecrolimus cream appears to be safe in both long- and short-term trials with equivalent or superior safety profile to topical corticosteroids.

These agents appear promising in their potential to make a dramatic impact in cancer prevention and treatment, with a significantly superior safety profile than most agents evaluated to date [ 4– 12].