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If confirmed in further research, particularly in a prospective study with sufficient incidence of T2D and CVD over time, the findings in these two studies suggest that the APOE rs439401 TT-genotype might be used to identify persons at high risk of developing T2D and/or CVD who might be targeted for preventive interventions.
The only location in Asia with sufficient incidence at the community level is in ethnic minority communities in Northern Thailand, where HIV incidence is currently in excess of 7%;[reference] thus they were invited to participate as well.
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However, we are unable to quantify their incidence with sufficient precision.
However, the impact of public transportation system on local spread of dengue in urban settings remains poorly understood, due to the difficulty in collecting relevant locality, transportation and disease incidence data with sufficient detail, and in suitably quantifying the combined effect of proximity and passenger flow.
This report describes research in a large insured population with sufficient size to quantify and compare the incidence rates of MI or CVA in patients with DME against matched diabetes controls.
With sufficient expansion, BIDS may be able to calculate population-based incidence rates for selected infectious diseases in some border areas.
All confirmed HIV-positive specimens with sufficient remaining sample were tested with Calypte HIV-1 BED Incidence EIA according to package insert instructions (Calypte® Biomedical Corporation. Calypte® HIV-1 BED Incidence EIA, Cat. No. 98003 March 2007); a cut-off level for OD of ≤0.8 was used to classify specimens as recent infections.
When comparing the first year with sufficient data to the following year, we found a decrease in the incidence of CAs from 5 to 4.2 per year (P = 0.3).
Prior to these trials, further epidemiologic information is needed about the incidence and burden of dengue worldwide to design trials with sufficient statistical power while minimizing any potential risks.
While scientists can examine some of these endpoints relatively easily in human populations (e.g. cancer incidence), others would be incredibly difficult to observe, measure, or prove with sufficient statistical certainty (e.g. feminization of boys or masculinization of girls).
The rising incidence of enterococci in biopsies from orthopedic patients is worrying, because of the limited number of antibiotics available with sufficient activity against this species.
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