Therefore, intact serum/plasma NMR spectra erroneously represent concentrations for many metabolites that bind or interact with proteins and such spectra, while useful for comparative studies, are not useful for the determination of absolute metabolite concentrations or comparing NMR data with that obtained by mass spectrometry.
PICKY has not been tested on spectra with dimensions higher than three, because such spectra data are not at hand.
Such spectra negatively interfere with all normalization approaches because they have an erroneously low TIC, vector norm, noise level, and median.
A set of 10,000 such spectra was used covering the whole range of monochromatic wavelengths, with different intensities and saturations.
However, even with such high spectrum efficiency (achieved only under optimum channel conditions) there is a large requirement of spectrum bandwidth.
Because they have a hard time grasping what another is feeling — a trait sometimes described as "mindblindness" — many assumed that those with such autism spectrum disorders were incapable of, or indifferent to, intimate relationships.
With such wide spectrum of nuclear receptors, which play a major role in maintaining normal physiological state and affect as diverse processes as development, reproduction, general metabolism, residing in Alus, it therefore becomes imperative to screen for variations in these sites.
Although the critical functions of ankyrins in the specialized membrane domains have been recognized for decades, the underlying mechanistic basis governing ankyrin's coordination with such broad spectrum of membrane targets remains essentially unknown, largely due to challenges in characterizing the biochemical and structural properties of the elongated ANK repeats.
Only a few proteins with such a doublet spectra, one being a δ-crystallin, are documented [37].
It was an odd experience to be among a group of business people with such a broad spectrum of products and interests.
