Sentence examples for with such significant from inspiring English sources

And to ensure that the proper time and consideration is given to a decision with such significant consequences.

Even with such significant price reductions, safaris are still not cheap.

With such significant usage, concerns for the security of data and personal information become paramount.

However, for anyone who has followed his career, there was no doubt that the chance to lead a club with such significant (if ancient) history would prove too difficult to refuse.

By using DHP in this way Scottish councils find themselves towards the top of the spend table compared to English councils, but with such significant differences in policy these comparative tables are almost redundant.

"It would be constitutionally inappropriate, not to mention setting a disturbing precedent, for the executive to act on an advisory referendum without explicit parliamentary approval – particularly one with such significant long-term consequences.

"The Wyss Institute is very proud to be associated with two such significant discoveries," said Donald E. Ingber, M.D., Ph.D., Founding Director of the Wyss Institute.

Sequences with no such significant hit were not considered in functional analyses (74% of viral data set and 50% of larger comparative data set).

However, with the election looming and with the presence of such significant issues becoming more prominent, it is becoming clear that this is not the case.

With such a significant detection rate of copy number variants, it is clearly important to decide whether MLPA should be employed before or after standard mutation analysis.

The Interior Ministry has yet to clarify exactly how it caught up with such a significant group in the middle of downtown Riyadh.