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If within each C2 domain's conformational repertoire there are distinct conformer subsets that mediate different molecular events of neurotransmission, then ligand and binding partner-induced selections of domain conformer combinations (with subtle refinements from other constituents of the protein's microenvironment) may permit the nuanced functions of Syt I observed in vivo.
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With the first exposure to the subtle refinements of the Vietnamese kitchen, the uninitiated American quickly puts aside any preconceptions of the food as being the same as Chinese.
With more than thirty years in the business, this luxury collection has mastered the subtle refinements that distinguish the upmarket price bracket.
He improved by making subtle refinements.
A Dream Outside, the debut album from London outfit Gengahr, doesn't quite mess with the formula as dramatically as any of those examples, but does offer its own subtle refinements.
The refreshing will include subtle refinements to the body and interior, the latest gadgets, maybe a new powertrain option.
iOS 9 once again brings many improvements, both small and large, including many subtle refinements that make your iPhone and iPad feel better and get things done faster.
Unless it concentrates on the numerous tiny details and subtle refinements required to produce truly fine cognac, it would never survive in the market.
Thus subtle refinements in the linguistic nuances of 7 items were made at this time.
The subtle refinement of Bronfman's style allowed him to weave ravishing spells in this inspired conversation between instruments, creating the effect of continually advancing or receding perspectives; duetting in turn with the lead cello, oboe, and horn, he gave as definitive a performance of this Olympian work as I ever expect to hear.
The shadow play and masked and unmasked dance are court arts reflecting centuries of subtle refinement under the patronage of kings and princes.
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CEO of Professional Science Editing for Scientists @ prosciediting.com