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The chemistry module was refined with subtle modifications to the chemistry procedure/unit and our experience with the unit is presented as an example of our approach to insure regulatory compliance.
While Moses' politics were objectionable, his methods were undeniably successful, and to this day designers continue to shape the behaviour and the character of urban centres with subtle modifications to the built environment.
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In particular, chimeric pestiviruses with substitution of the entire E2 protein have been described [ 15- 17] but also mutants with more subtle modifications, such as the modification of the important TAV-epitope [ 18] within the CSFV-E2 protein [ 19, 20] are promising marker vaccine candidates.
In addition, the unexpected observation of the binding of the dual inhibitor at the secondary site of C-ACE, FII-B, (involving displacement of conserved water molecules), provides further leads to be explored with regard to subtle modifications of the chemical space at the active site.
Mosler says the car's 5.7-liter Corvette engine has "subtle modifications" and teams with a six-speed manual transmission.
In this respect, the Dcx KO mouse is unique, exhibiting subtle modifications of the hippocampal circuitry, associated with the susceptibility to epilepsy.
The ability to identify important yet subtle modifications of lipid A is imperative for correlating immune responses with lipid A structures.
To the untrained eye, these are subtle modifications.
They are able to do this through subtle modifications of the pattern and fit of their otherwise standard garments.
Subtle modifications were incorporated into the structure of clinical candidate 1.
In 2007, the Acute Kidney Injury Network classification was published, introducing subtle modifications to the RIFLE criteria.
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