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The upgraded mice squeaked somewhat differently from plain mice and were born with subtle alterations in brain structure.
Further well designed, prospective studies are required to assess the validity of skeletal scintigraphy as a diagnostic tool, particularly in horses with subtle alterations in radiopharmaceutical uptake.
Becker, Axel et al. "Transient prenatal vitamin D deficiency is associated with subtle alterations in learning and memory functions in adult rats". Behavioural brain research 161.2 20055): 306 312.
In a study of 4,466 people between the ages of 71 and 81, researchers found that even a limited alcohol intake of two or more servings a day for men and one or more for women was associated with subtle alterations in cardiac structure and function.
Instead, the data was more consistent with subtle alterations in the expression of multiple genes potentially coupled with extensive differences in a limited set of transcripts.
Reductions in fibroblast glucosylceramidase activity are associated with subtle alterations in lysosomal biochemistry.
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First, the absolute ratio of Tregs to self-reactive T cells may be critical, with relatively subtle alterations resulting in disease.
Our results escalate this surprise further as genetic deletions of the neuronal enzyme TPH2 and the combination of TPH1 plus TPH2 enzymes also produced viable mice with relatively subtle alterations in behavior.
This suppressive effect correlates with a subtle alteration in B-cell development induced by the immunoglobulin transgene.
Developmental vitamin D deficiency is associated with a subtle alteration in the expression of protein involved in functions related to calcium binding proteins, and mitochondrial functioning.
Ms. Feuerman, who lives and works in Manhattan, says that with each casting she makes subtle alterations: "I change the nose, or the angle of the face".
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