Sentence examples for with substantial risks from inspiring English sources

Despite the merits of such an idea, a one-off levy is far from an easy solution and comes with "substantial risks," the central bank said.

But in a part of the country where mining tragedies have struck so many towns, they know that the $20-an-hour 20-an-hour 20-an-hourubstantial risks.

Emma Gray, head of clinical trials at the MS Society, said: "This treatment does offer hope, but it's also an aggressive procedure that comes with substantial risks and requires specialist aftercare.

One message of what happened is that quantitative easing (the official name for the policies being carried out by the Japanese central bank, and by the Federal Reserve here), while justified given the circumstances, does come with substantial risks attached.

Dr. Brian L. Strom, a professor at the University of Pennsylvania School of Medicine who was chairman of the committee, said that the panel was urging caution because "it does not make sense to give a vaccine with substantial risks against a disease that does not exist -- in fact, that could be considered unethical".

This study investigates whether the impact of history of incarceration on ED use is mediated by opiate use and sex trading for drugs or money, two current public health problems with substantial risks to individual health.

In other situations, the isolation may reflect colonisation, but given that colonisation itself is associated with substantial risk of subsequent infection[7] [9] and that there has been a clinical indication for taking a specimen (as opposed to a screen of an otherwise healthy appearing individual), its inclusion in a surveillance measure may be justified.

In florid relapse, however, the efficacy of DLI is limited with substantial risk of severe graft-versus-host disease (GvHD).

Similarly, all men < 30 years with substantial risk factor burden using the Framingham risk score model also reported low risk using existing threshold [ 65].

Overall, the evidence is sparse and inconclusive due to several low-quality trials with substantial risk of bias and the heterogeneity of examined populations and interventions' [ 18].

For some patients, however, surgery is associated with substantial risk either because of a discharging sinus or proximity of facial nerve branches.