Sentence examples for with substantial changes from inspiring English sources

"The departure of these three individuals together with substantial changes in operating procedures allow KPMG to begin with a clean slate.

Mr. Willimon later wrote a play on which "The Ides of March" is based, with substantial changes by Mr. Clooney, Mr. Willimon and the other writer, Grant Heslov.

The screenplay was adapted from one of Mr. Roche's stories, with substantial changes — Michael's wife has been killed off and a pinch of the supernatural has been tossed in — though someone forgot the connective tissue.

The work went through three editions within 5 years, each with substantial changes.

Pregnancy is associated with substantial changes in the maternal circulatory physiology.

The succession from pine to oak forest was associated with substantial changes in microbial community structure and functioning.

Such a phenomenon has been observed in specific disease systems, but with substantial change in global land use projected for this century, assessing its global and taxonomic generality would shed light on an important hypothesised driver of environmental synergies or trade-offs between conservation and public health.

Irrespective of the exact processes contributing to this result, we have demonstrated that geographical marginality can be associated with substantial change in P.

In this work, 'photosynthesis-antenna proteins' and 'photosynthesis' are two major GO terms that were associated with substantial change in transcript levels in response to cold stress.

Simultaneously, the proportion of responders (subjects with PGA = 1 or 2) increased every 4 weeks, with more substantial changes for alitretinoin 30 mg once daily than placebo or alitretinoin 10 mg.

Unplanned large scale developmental projects in recent times have been causing alterations in land use land cover [LULC] at spatial and temporal scales with the substantial changes in the landscape.