Sentence examples for with significant drawbacks from inspiring English sources

Taking a principled drive, though, comes with significant drawbacks.

Pathogens have been implicated for decades as potential anti-cancer agents, but implementation into clinical therapy has been plagued with significant drawbacks.

Rolling elements were found to be the most slippery, providing a coefficient of friction as low as 0.03, but with significant drawbacks from the perspective of our design objectives.

Additionally, there are several specific reasons to suspect that Sanger confirmation of all clinically relevant SNVs detected by NGS is an unnecessarily conservative approach with significant drawbacks.

However, the model comes with some significant drawbacks.

In contrast to the standardized microbial and mammalian cell platforms embraced by the biopharmaceutical industry, there are many different plant-based expression systems vying for attention, and those with the greatest potential to provide inexpensive biopharmaceuticals are also the ones with the most significant drawbacks in terms of DSP.

So why, if the evidence for the disorder is so shaky, and if the medication has significant drawbacks, with NICE explicitly not recommending drugs as a first-line treatment for school-age children, is Ritalin prescription on an ever-increasing curve?

There may be significant drawbacks with this method, however.

Heatmaps do, however, have significant drawbacks with regards to color perception.

Significant drawbacks with closed suction systems include risk for producing high negative pressures and reduced efficacy in removing thick secretions from the airways [ 2, 11, 12].

But a new study finds that a commonly used antibiotic works much better than cranberry, with one significant drawback: It encourages the development of resistant strains of bacteria.