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This observation is consistent with sequence alignment of the different genes.
Multiple sections of highly similar sequences may well explain some of the difficulties that were encountered with sequence alignment of the MHC reference.
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With sequence alignments of the meq, pp38, and gB genes of strain AH1410 and other MDV isolates, we found that GX0101 and AH1410 are completely identical in these three genes.
BWP conceived the phylogenetic analyses, and assisted with sequence alignment, interpretation of data and revision of the manuscript.
Overall, the principal theme underlying the inconsistencies identified is repetition: as with sequence alignment the existence of strongly periodic structures creates ambiguities for alignment.
Secondary structure prediction was produced with the PHD program [ 27], with multiple sequence alignment of FBG domains.
However, a BLAST search with the sequence alignment of their products revealed that only llmg 0899 truly encodes protein uS15.
Figure S2 shows the domain analyses for L. monocytogenes, together with a sequence alignment of B. subtilis RsbRA-D.
The GOPubMed classifier is not scientifically described, but the tool is supposed to work with 'local sequence alignment of words of the abstract and the words of GO terms' (18).
We discuss the resulting problems with sequence alignment, phylogenetic analysis, and tests of selection.
Given a rooted phylogenetic tree and an ancestral sequence we generate evolved sequences for each internal and leaf node of the tree, along with a multiple sequence alignment of regions conserved throughout the simulated evolution.
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CEO of Professional Science Editing for Scientists @ prosciediting.com