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Author's Note: the case of Southwest Elementary, along with a similar example out of Rockville Centre High School in Long Island, NY, is documented by William Darity, Jr. and Alicia Jolla in "Desegregated Schools with Segregated Education," in Hartman, Chester and Gregory Squires, The Integration Debate: Competing Futures for America's Cities.
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When comparing families with segregating and non-segregating MHC genotypes, the mean total parasite load of non-segregating families was not significantly different (F1,52 = 0.506, P = 0.480).
Bulk segregant analysis is a method in which individuals in a population with segregating phenotypes are sorted into pools and then genotyped for associated molecular markers.
This result is not consistent with those of previous studies showing that the proportion of the phenotypic variance that could be explained by the markers was greatly enhanced in the NIL population compared with segregating populations, such as BILs.
Why are we okay with segregating by gender?
Not all are on board with segregating boys from girls in the classroom, however.
However, the parental phase for 98 markers with segregating polymorphisms was unknown.
As was observed for the WILD2 cross, segregating genotypes for E24C3 were strongly associated with segregating sex phenotypes in MEX1.
An additional 353 genes scattered throughout the genome were regulated in trans by loci that coincided with segregating CNVs.
Genotyping with molecular markers allows the visualization of recombination patterns which is crucial for the elucidation of loci associated with segregating traits [ 10, 11].
For sites with segregating variation, are disease risk alleles relatively common (e.g. with minor alleles at frequencies of 1%, or 5%, or above) or more rare?
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