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The latter were designed in such a way that they do not interfere with routine practice; clinicians routinely gather all relevant data using validated instruments (e.g., pain severity, disability, etc)., and introduce them in a software package specifically designed for that purpose [ 40- 43].
Cluster randomised trial comparing Targeted case finding (28 practices) with routine practice (28 practices).
The CT scans were initially assessed by local hospital radiologists, consistent with routine practice.
To fully understand the potential benefits of new therapeutics in RA, outcome measures must be integrated with routine practice.
Taking extra precaution in measurement techniques in trials, when being observed, compared with routine practice has been termed the 'Hawthorne effect' 16, 17.
The uterine incision-to-delivery interval is prolonged compared with routine practice, but usually still within the 3 minutes formerly recommended for optimal neonatal condition.
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Tests for FBG were carried out in all patients in line with the routine practice in the hospital.
Also, the limits of acceptable CK and transaminase elevations in these studies are certainly higher than most physicians would be comfortable with in routine practice.
Patients were treated in accordance with the routine practice of the respective institution, and findings were prospectively documented on standardized case report forms.
Effectiveness and tolerability were recorded at an initial visit and one or two follow-up visits, with scheduling carried out at the discretion of the treating physician in line with daily routine practice.
In our study, however, MPA dosing, decreased posttransplant and was, at all time points, significantly lower in patients randomized to Tac compared to CsA, in agreement with common routine practice to reduce differences in exposure.
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