In these cells the β1-integrin function-blocking antibody, which restores the β1 level present in normal tissue, caused a reversion to a normal phenotype with functionally polarized acinus-like structures, and this occurs only in three-dimensional cultures [ 5, 13, 27, 37].
First, in this cell system, QNR/v-srcts cells reversion to a normal phenotype, in presence of an active v-Src, is compatible with their sustained division.
We also report that reversion to a normal 14-3-3η 14-3-3η 14-3-3η.19 ng/ml) wastateociated with better clinical outcomes.e
In an experimental study, transfection of antisense N-cadherin into a cancer cell line with a scattered fibroblastic phenotype resulted in reversion to a normal-appearing squamous epithelial cell, interestingly, with increased E-cadherin expression (Islam et al, 1996).
Increased β-cell function and insulin resistance were significantly associated with reversion to normal glucose tolerance and inversely associated with the risk of developing diabetes.
CVD risk factor values and changes from baseline became more unfavorable as glucose tolerance status deteriorated but improved with reversion to normal glucose tolerance (NGT), especially in the ILS intervention group (trend test P < 0.001 for all risk factors except for LDL PPD [ P = 0.02] in ILS and HDL cholesterol [ P = 0.02] in placebo).
A reversion to a more normal collagen phenotype, measured as an increase in fibril diameter and restored fibrillar architecture, and a decreased rate of collagen turnover were seen in cells expressing the ribozyme multimer.
Definitions used were: A normal tympanogram Reversion to normal audiometry Normal otoscopic findings Parental view (improvement/lack of problem).
A third possibility is transient seroconversion with reversion to seronegative status (5, 6 ).
blaNDM-1 gene deletions correlated with reversion to ertapenem susceptibility.
