Sentence examples for with respect to its functioning from inspiring English sources

More importantly, must such alleles, for any common disease, represent slightly malfunctional cogs in our human machine with respect to its functioning overall, or might they also be advantageous, at least in some contexts?

In this paper we show that BRCA1 can discriminate between different types of DNA damage and we discuss the implications of this with respect to its function in DNA repair.

With respect to its function, MALAT1 is localized to nuclear speckles and has been associated with regulation of gene expressions [ 19, 20].

In this study we focus on the proximal promoter region (PR) of the ppcA1 gene with respect to its function in establishing the C4-characteristic expression pattern.

With respect to its function, there is convincing evidence that PLK1 is essential in G2/M-phase transition of both normal and malignant cells.

However, an artificially constructed peptide based on these pseudogenes, called retrocyclin, has been studied with respect to its function and therapeutic potential and shown to kill Escherichia coli in the same way as α-defensins, by permeabilising its membrane [ 44].

In this review, we discussed the effect of the vasa vasorum on the progression of atherosclerotic plaques with respect to its function not only as a conduit structure that delivers blood components, but also as a stem cell reservoir.

"One of the issues that we're certainly concerned about is the way the business was run … We certainly take a view that the QN operation with respect to its treasury function was run in a reckless fashion".

The orbitofrontal cortex (OFC) may be involved in the clinical and cognitive expressions of obsessive-compulsive disorder (OCD) and is a heterogenous region with respect to its cytoarchitecture, function and connectivity.

With respect to its mitochondrial function, recent reports have given some clues.

The motions of His221 observed in the simulations were in agreement with these results and allowed interesting conclusions regarding the role of His221 in substrate recognition and with respect to its chaperone function in guiding E1 out of the SUB (Figure 7).