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This rearrangement of H-bonds coincided with regularisation of the bulge.
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Our main conclusion is that, even with regularisation, many distinct history matched models are possible, which highlights the importance of applying optimisation methods capable of identifying all such solutions.
The simulation with NMR2-2K3A* demonstraned alternativeive regularisation of β2 that was achieved while maintaining the H-bonding partners of V224, R226 and H228 (Figure S5B).
The model parameters were determined from the experimental data by using the least squares fitting with regularisation.
Even with regularisation, performance may be still be affected by over-fitting, which may explain the slightly reduced accuracy.
A generalised linear regression method with regularisation and variable selection was applied within a multiple covariate Cox survival analysis with the aim of finding expression profiles correlated with recurrence-free survival.
The GN and NNLS algorithms have been implemented to solve Eq. (8): (8) x = min x ‖ y − Jx ‖ 2 2 + α ‖ Ix ‖ 2 2 such that x i ≥ 0 which includes identity-matrix-based Tikhonov regularisation with regularisation weight α.
A generalised linear regression with regularisation and variable selection was applied to a multiple covariate Cox survival analysis with recurrence-free survival 10-fold cross-validation and leave-one-out iterative approach were used to build and test the model that was validated using an independent cohort of 58 patients with pure DCIS.
It demands the regularisation of working conditions in the sex industry in line with other comparable businesses and calls for the creation of social services for sex workers.
The selectivity was indicated by the regularisation of clotting by lipopolysaccharide-binding protein (LBP).
Bouncing on, he criticises the church's campaign for regularisation of immigrants, and Islam's "adversarial quality".
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