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Specifically, we randomly permuted the assignment of significance (with regards to exercise) among the 596 aging-related genes, and calculated the total distance (relative to young) of the resulting log2 ratios (old-exercise over young) of the genes significantly related to exercise by simply summing up squared log2 ratios (Figure 3).
With regards to exercise they were instructed to walk briskly for 30 min, at least 5 days per week, in accordance with the American Diabetes Association Position Statement [ 31] and this was monitored by 7-day pedometry.
This offers valuable information for those wishing to employ a similar intervention with regards to exercise duration, with improvements occurring earlier than the findings of Prosperini et al. [ 14] suggest.
While the experiences of some couples in this study were in accordance with these findings, we found that only spouses who had their own history of 'voluntary' physical activity participation were receptive to spousal role modelling with regards to exercise.
We have identified a single study addressing the role of a CD-ROM as a tool to provide information to pregnant and post-partum women with regards to exercise [ 38].
In addition, RCTs usually start from an assumption of equipoise -- i.e. a position of not knowing which of two competing interventions is more effective, or not knowing whether an intervention is likely to be beneficial or harmful [ 17] -- but this position is not clear with regards to exercise referral schemes.
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With regard to exercise, the lesbians were significantly more likely to exercise at least weekly.
It could also be questioned whether spontaneous, thus uninstructed, entrainment is generally more beneficial with regard to exercise performance than instructed entrainment.
They are not too demanding with regard to exercise; their inbred stamina means they do not easily tire when exercised, but they also do not need to be worked to exhaustion before they will rest.
NDM differed from the other diabetes status groups with regard to exercise.
However, lack of reported detail of the exercise component limits further comment of these findings with regard to exercise prescription.
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