Exact(52)
Selective NR1-Gly antagonists have been claimed to reduce pain with reduced side effects [ 87, 88].
Such nanotechnology platforms allow the development of cancer diagnosis and treatment that is more effective with reduced side effects [2, 3, 5, 6, 7].
More effective therapies, with reduced side effects, are highly desirable.
For therapy, PTT, PDT, and drug (or gene) delivery have proven to be efficient and effective methods with reduced side effects to normal tissues, where the surface engineering plays an important role in the therapeutic efficacy.
To decrease the current cancer burden, drug discovery is directed at the development of highly effective and potent medications with reduced side effects.
Recently discovered endomorphin-1 (Tyr-Pro-Trp-Phe-NH2, EM1) and endomorphin-2 (Tyr-Pro-Phe-Phe-NH2, EM2), which display high affinity and selectivity to mu-opioid receptors, proved to be effective against neuropathic and inflammatory pain with reduced side effects [ 1, 2].
Similar(8)
This work revealed a strategy for the design and preparation of anti-cancer drug delivery systems with reduced side effect, enhanced anti-tumor and anti-metastasis efficacy.
More specifically, N-selective (N-domain-selective) inhibition could allow for the treatment of tissue injury and fibrosis diseases without affecting blood pressure and with reduced side effect profiles (Table 1).
In spite of significant progress in design and application of CPP, more investigations are required to further improve their delivery to tumors, with reduced side-effect and enhanced therapeutic efficacy.
Consequently, larger amounts of monomeric variants could be used as an allergy vaccine with reduced side-effects to induce production of protective IgG antibodies.
A sub-set of solutions related to changes to medication, including simplification of the regimen, the development of better drugs with reduced side-effects, and improved packaging, and often referred to the tailoring of dosage to individual need and to compatibility with the patient's lifestyle.
Write better and faster with AI suggestions while staying true to your unique style.
Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com