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Compounds 19b, 19d and 19p displayed clear dose responsiveness in the lymphocyte reduction model when administered orally at doses of 0.3, 1.0, 3.0 mg/kg with reduced effect on heart rate.
Multiple mating is a low variance strategy that works more often, but with reduced effect.
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In the present study, we propose a method for automatic selection of a proper parameter for imaging blood flow in an unknown velocity region with reduced effects of speckle contrast and random noises.
First, the increased levels of diversity at the intergenic loci chosen in the current study as compared to the levels of diversity at loci in the compiled dataset are consistent with reduced effects of background selection and genetic hitchhiking in these regions.
High cPLA2 α expression decreased overall survival in patients with luminal cancers, and correlated with a reduced effect of tamoxifen treatment.
In sharp contrast with the reduced effect of socioeconomic status and cultural background, the effect of grade of school is greatly significant on enrollment in senior high school.
Seventy percent of the subjects mentioned that the anesthetic effect lingered with a reduced effect for 30 min after completion of the study, while 30% of the subjects reported complete absence of anesthetic effect after 30 min.
More generally, conditions that allow high parasite loads with a reduced effect on host health could result in poorer detection of infection, compromising disease control efforts [ 14].
Generally, although population studies have shown that plasma homocysteine is higher in TT individuals (43), this effect is modified by folate status a high folate status is associated with a reduced effect of MTHFR 677C>T on homocysteine concentrations (44– 44).
In fact, SPME technique permits a selective extraction of the target organic compounds not adsorbed by the NPs directly into the reaction vessel, with a reduced effect on the interaction between NPs and probe compounds.
Conversely, recent studies provide evidence that continuous infusion of low-dose terlipressin exerts beneficial hemodynamic effects with reduced side effects as compared with traditional bolus injection.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com