Sentence examples for with prolonged effect from inspiring English sources

For some parenterally administered active compounds a differentiation is made between immediate release preparations and those with prolonged effect [ 20].

This led to the development of insulin preparations with prolonged effect, described as 'intermediate-' and 'long-acting' insulin formulations (Fig.  1) [ 53].

MAC allows: - the modulation of the level of analgesia at different stages of surgery due to the availability of analgesic action, but with rapid onset-time - the additional analgesia using local anesthetics with prolonged effect without the use of noradrenaline, dangerous for elderly patients the consciousness and cooperation of the patient (Table 1).

Some 44 genes showing >2 fold changes are listed in Table 7 and 8. Overall, changes in expression levels were greater for metabolism genes than for genes in other pathways, with prolonged effects lasting up to 12 h.

In addition, d-serine has been identified as a critical regulator of postnatal development in other CNS regions, specifically influencing NMDAR participation in synaptic activity with prolonged effects.

11 Through direct binding with matrix metalloproteinase-9 (MMP-9), NGAL inhibits its inactivation by tissue inhibitors of matrix metalloproteinase-1 (TIMP-1) and leads to its enhanced proteolytic activity with prolonged effects on collagen degradation.

The association between menarche and diabetes may exist because early menarche may be a marker of higher prepubertal BMI, with prolonged effects of increased adiposity being the main risk factor for diabetes.

Introduction of BAC directly to the polymer matrix leads to a very rapid release (Fig. 6, curve 1), which is undesirable since our aim is to create materials with a prolonged effect.

Seasonal IPT reduced the prevalence of anemia by 30 45%, but with no prolonged effect beyond the intervention period [10].

Interestingly, the effect observed with the mixed compound was similar to that observed in animals treated with indomethacin, but with a more prolonged effect (for up to 24 h).

Distributed lag models exhibited a different risk pattern between the United States and Europe, with a more prolonged effect of exposure to PM10 seen in the United States.