Sentence examples for with potency in from inspiring English sources

Three new hits were predicted with potency in the submicromolar range and presented drug-like properties.

Raltegravir inhibits the strand transfer function of HIV-1 IN with potency in the low nanomolar range.

Structure- and property-based design approaches are actively used to identify inhibitors capable of targeting all Pim family members with potency in the nanomolar range.

All fusions and an S249C mutant FGFR3 positive control induced anchorage independent growth with potency in the order: RT112FUS > RT4FUS > S249C > SW780FUS.

Two of the compounds block the growth of malaria in culture with potencies in the sub-micromolar range.

All studied MC4 receptor-specific nonlabeled ligands displaced fluoroligands' binding in a concentration-dependent manner with potencies in agreement with their pharmacological activities.

Indeed, such inhibitors of the sulfonylated amino acid hydroxamate type have been generated, with potencies in the low nanomolar range for both type of enzymes, CAs and MMPs.

A new class of 2-oxo-tetrahydro-1,8-naphthyridine-based protein farnesyltransferase inhibitors were synthesized and found to inhibit protein farnesyltransferase from the malaria parasite with potencies in the low nanomolar range.

Viral neutralizing monovalent VHH, with potencies in the micromolar range, were generated by immunization of llamas with recombinant trimeric envelope spike proteins or with (inactivated) virus from three different viruses, RSV, Rabies virus and highly pathogenic Influenza H5N1 virus.

The screen gave a number of compounds with potencies in the 100 500 μM range, that is, similar to the parent compound.

While a handful of leads have been discovered with potencies in the nanomolar range, there is typically limited selectivity over the human homologue, and host cell toxicity effects are variable.