In WT mice, β-catenin was very weakly expressed in the colonic crypts with more notable expression in the colonic plate/luminal surface of the mucosa.
From functional studies with her patients she knows that the prefrontal cortex might be involved and decides to focus on genes with a notable expression there.
Taking together, whereas the high expression of these genes with unknown function in the hypothalamus again suggests a role in central energy regulation, LYPLAL1 with its notable expression in the kidney fat and the differences between ZDF and ZL rats implicates also a role in the adipose tissue itself.
Indeed, we have previously shown that intracerebral lesions of Mel57, a human melanoma cell line with no notable expression of VEGF-A, were not detectable in Gd-DTPA MR images, yet were visible in T2 images after intravenous injection of USPIOs (Leenders et al, 2003).
Compared with the pGPR120-V3, the notable expression of pGPR120-V2 in the spleen as well as the porcine macrophage cell 3D4/2 was observed, naturally suggesting that this alternative spliced isoform might act a role of inflammation in that tissue.
Prepartum diets were associated with notable gene expression changes in fetal tissues.
Finally, sequencing individual placentas allowed us to reveal notable expression similarity between littermates.
BMP6 was chosen because of its notable expression levels in RA synoviocytes and its high upregulation after synoviocyte stimulation with pro-inflammatory cytokines (Figs. 1b and 3b).
Recently, Antonescu et al reported that human angiosarcomas have unique gene expression profiles when compared to other soft tissue sarcomas [ 56], with notable enrichment of expression of vascular-specific receptor tyrosine kinases TIE1, KDR (VEGFR2), SNRK, TEK, and FLT1 (VEGFR1), and other genes that are prototypical endothelial markers including EPHA2 and PDGFβ.
