Exact(31)
The human voice undergoes changes associated with normal physiological aging after the age of approximately 65 years.
However, in situations where ROS production exceeds the cell's antioxidant capability, cell death can occur by interfering with normal physiological processes and the modification of cellular biomolecules [28].
The Latin American doctors argue, however, that they're not being treated as humans with "normal physiological needs", says another Mexican doctor, Marcela Cueva.
Since the response is directed specifically to misfolded Aβ, it is unlikely that vaccination will interfere with normal physiological processing of the amyloid precursor protein.
This parameter provides an opportunity for the design of anthrax inhibitors which would inactivate extracellular furin without interfering with normal physiological functions of cellular furin and furin-like PCs.
One explanation is that while these changes prevent AR signaling from promoting either survival or proliferation of malignant prostate cells, the lack of AR signaling eliminates the growth suppression normally induced by AR signaling in non-transformed prostate epithelial cells in a host with normal physiological levels of androgen.
Similar(29)
We used an in situ approach where the TA muscle is kept in the most physiologically relevant environment possible, within normal physiological temperature range, with intact motor neuron innervation and vasculature [17].
In most crop plants, the main toxic component of salinity is Na+ and Cl-, whinterfereseres with the normal physiological processes, such as enzyme activities and protein synthesis, as well as causing osmotic imbalances (Munns and Tester 2008).
The pH-sensitive systems are of special interest because tumors and intracellular endosomal/lysomal compartments exhibit abnormally high local acidities compared to healthy tissues with a normal physiological pH of 7.4 [9, 21, 25, 28 43].
The study is the first to show in mammals that "autophagy is clearly connected with a normal physiological process, which is birth," says cell biologist Daniel Klionsky of the University of Michigan, Ann Arbor.
A disadvantage of a vaccine against the N-terminus of Aβ is that it will interfere with the normal physiological processing of APP.
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