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Only one of the trials with no observed reduction in pain intensity had sufficient internal sensitivity.
Four [ 27, 31, 34, 36] of the six trials with no observed reduction in pain intensity had sufficient internal sensitivity.
Three [ 27, 31, 36] of the five trials with no observed reduction in pain intensity had sufficient internal sensitivity.
Therapy was well tolerated (overall grade 3 toxicity occurred in 48% patients; no grade 4 nonhaematological toxicity was reported), with no observed late toxicities.
After 4d exposure to SWCNT, algal growth was inhibited at LOEC 0.25 mg/L in the presence of 0.023% (v/v) GA, while the double concentration of GA reduced this effect with No Observed Effect Concentration (NOEC) 0.5 mg/L.
The agent was then observed to be excreted via the kidneys with no observed toxicity.
This patient was observed in the hospital overnight and discharged the next day with no observed short-term complications.
Compound 35 was orally active in tumor models with no observed toxicity.
The needle entered smoothly, with no observed bleeding, paresthesia, or pain.
Similar(2)
Toxic substances under REACH are those with no-observed effect concentrations (NOECs) below 0.01 mg L−1 or substances classified as being carcinogenic, mutagenic or toxic for reproduction for humans according to regulation EC No 1272/2008.
Unbiased concentration response effects with no-observed-adverse-effect levels (NOAELs) were demonstrated for three different definitions of gastroenteritis and four fecal indicator organisms.
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