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In patients with no kidney disease prior to admission to ICU, both pNGAL and uNGAL have a fair predictive value to diagnose the occurrence of AKI for up to 72 hours.
The groups of patients with no kidney dysfunction or at risk of kidney injury on admission who received HES were more severely ill; in particular, they had more cardiovascular and respiratory failures.
In patients with no kidney function, alkali addition gain or acid losses increase serum bicarbonate levels, and the excess alkali is retained until it is consumed eventually by endogenous acid production [ 1].
We analyzed the modes of failure, prevalence of migration, and rates of revision of bipolar hemiarthroplasty in patients on long-term hemodialysis and compared the results to those from a match-paired group of patients with no kidney disease.
A large population-based cohort study of nonspecific critically ill patients (5693 admissions) showed that any kidney dysfunction is associated with an increased risk for long-term death, with the exception of ESRDPos patients, who had outcomes similar to those of patients with no kidney dysfunction [ 13].
In a previous issue of Critical Care, Matsa and colleagues [ 1] suggest that, in patients with no kidney disease prior to admission to the ICU, both plasma (pNGAL) and urinary (uNGAL) neutrophil gelatinase-associated lipocalin have a fair predictive value to diagnose the occurrence of acute kidney injury (AKI) for up to 72 hours.
Similar(54)
If you drink a bottle of brandy you turn into a monster and one day you'll wake up with no kidneys and cirrhosis of the liver.
After receiving losartan treatment, no significant differences were found for levels of activated RAS, fibronectin, and α-SMA in O kidneys compared with NO kidneys, 2 e) and 2(f), resp ., and a similar pattern was observed for pERK1/2 and pAkt and 2(c), resp).
In my case, and most people with next to no kidney function, you have to restrict the intake to a litre a day.
On the less severe end of the spectrum, Senior Løken syndrome primarily involves only retinitis pigmentosa and nephronophthisis, a cystic kidney disease that involves kidney malfunction with little to no kidney enlargement (figure 2g; Hildebrandt and Zhou 2007).
In addition, survival was significantly poorer in patients with mild acute kidney injury (stage 1) compared with no acute kidney injury, and that it worsened with increased severity of acute kidney injury.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.
Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com